Endocrine Abstracts

Introduction: Extra-adrenal paragangliomas are neoplasms arising from cells of neural crest origin anywhere along the distribution of the sympathoadrenal neuroendocrine system. Nearly 85% are intra-abdominal, 12% are intrathoracic, and 3% are cervical. 1 Some of the unusual sites for paragangliomas include the kidney, urethra, urinary bladder, prostate.Case report: A 27-year old man presented with sever hypertensive crisis. He had a medical history of hi...

Introduction: In Tunisia, only about 10% of people with diabetes practice self-injecting insulin analogues. It is 1 Tunisian adult out of 11 who is affected directly by diabetes. Our goal is to assess diabetes patients’ knowledge of insulin injection techniques.Patients and methods: Prospective study of 56 cases of type 2 diabetic patients in the Endocrinology Department CHU Hedi Chaker Sfax Tunisia. All patients had a questionnaire and clinical exa...

Introduction: Pituitary abscesses are rare entities that can occur either as primary infections or secondarily to different causes. Primary pituitary abscess arises within a previously healthy gland, while secondary abscess occurs in pituitary gland that harbors a pre-existing lesion (adenoma, craniopharyngioma, or Rathke’s cleft cyst). Only 23 cases of secondarily infected adenomas were reported in the literature.Case report: A 38-years-old man pre...

Introduction: The association of primary hyperparathyroidism (PHPT) and hyperthyroidism secondary to toxic multinodular goiter (TMNG) is rarely described in the literature. Hereby, we describe the clinical, biological, and radiological characteristics of two patients having this rare association.Observations: First case: A 66 years-old female was diagnosed with primary hyperthyroidism. Her thyroid antibodies were negatives. During the follow-up, she pres...

Introduction Multiple autoimmune syndrome (MASI) is a rare entity, defined by the presence of at least three autoimmune diseases in the same person. We report two specific observations of myasthenia gravis in the context of an SAIM3. Observation 1 A 58-year-old man initially presented bilateral ptosis, difficulty chewing and swallowing, dysphonia and fatigability. Myasthenia gravis was suspected due to the ag...

Introduction: The chrono-type, intrinsic to each individual, is the tendency of an individual to prefer activities carried out in the morning or evening. The aim of our study was to determine the chronotype of our obese patients.Materials and methods: This is a descriptive cross-sectional study involving obese adults consulting the service of Endocrinology of Sfax, Hedi Chaker University Hospital, during the period extending from December 2022 until Marc...

Introduction: Thyroid eye disease (TED) is the major extra-thyroidal manifestation of Graves’ disease (GD). The delayed onset of TED after hyperthyroidism resolution and the decline in TRAb levels is a rare occurrence, necessitating the exclusion of other underlying orbital inflammatory diseases.Case Report: A 59-year-old non-smoking female patient presented with thyrotoxicosis symptoms (fatigue, palpitations, resting tremors) persisting for three m...

Introduction: Hypoparathyroidism (HPTH) is an uncommon condition resulting in the production of insufficient amounts of parathyroid hormone (PTH) by the parathyroid glands consequently affecting the calcium phosphate balance. The most frequent etiology of HPTH is the damage to or removal of the parathyroid glands due to a surgery for another condition. Other causes, including autoimmunity and genetic disorders may be responsible for HPTH. Our aim is to compare the different cl...

Objective: To test the reliability of the classic diabetic survey (DS) in the diagnosis of malnutrition in elderly patients with diabetes mellitus (DM).Patients and Methods: Analytical study of 55 patients aged over 65 years who were hospitalized in the Endocrinology Department. A DS was performed for all patients. The diagnosis of malnutrition was established according to the criteria proposed by the HAS 2021. Two subgroups were compared: G1 (n...

Introduction: Anemia is defined by the World Health Organization as a hemoglobin concentration less than 120 g/l in women outside of pregnancy, and less than 130 g/l in men over 15 years of age. It is common in diabetics. It can be due to an autoimmune disease associated with type 1 diabetes, whereas the inflammatory cause is the primary cause in type 2 diabetes.Observation: This is a 75 year old patient, type 2 diabetic for 21 years on insulin analogues...